Sickle Cell Disease

THE PROBLEM

Sickle Cell DiseaseĀ (SCD)

  • The most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans
  • World wide, about 4.4 million people have sickle-cell disease, 80% of the cases occurring in sub-Saharan Africa

Sickle Cell Disease is an inherited form of anemia

  • SCD is caused by a mutation which causes red blood cells to be irregularly shaped, like a sickle, and unable to transport oxygen properly
  • In the United States, about 1,000 children are born with the disease every year
  • If the mutation could be corrected, the disease could be cured

Typical symptoms of SCD include:

  • Anemia/Fatigue
  • Episodes of pain
  • Organ damage

Cost of Treatment

  • The annual cost to treat SCD is $10,000 for children and $30,000 for adults
  • The lifetime cost of care is approximately $450,000 to $1M per patient